FILTERS:
pvalue:1.0
Region for Gene AH6.5
Go to Ensembl.org Go to UCSC

This page describes one promoter-based search region.

Page Contents

Overview
Genomic Context
Image of Motifs and Modules
Motifs Found in this Region
Search region overview
Search region location CHROMOSOME_II:9,522,596-9,524,095 (+) (1500 bp)
Assembly C.elegans, Ensembl v45 (WS170)
WormBase ID AH6.5
Modules
(Co-occurring motif patterns)
No annotation-based modules were found.
No 'de novo' modules exist in this database.

Genomic Context: C.elegans genome assembly from Jan 2007. (UCSC ce4, WS170, Ensembl v45)

The image shown below was created to provide context for this search region by showing a 100000 bp span of the genome, centered on this search region.

UCSC Genome Browser Image    
  • The first track shows the location of the search region in red.
  • The last track shows known gene locations in this 100000 bp span of the genome.

This promoter-based search region is located close to a particular gene of interest, described in the table below. Click on the gene id to open a page at ensembl.org with more information about this gene.

Target gene used to create this search region
WormBase ID AH6.5
Gene location CHROMOSOME_II: 9,524,096-9,525,790 (+) (1,695 bp)
Distance from the region's midpoint to TSS -749
The distance from a cisred search region to a gene, is measured from the center of the search region to either the transcription termination site (TTS) or the transcription start site (TSS), whichever is closer.
A distance is negative if the TTS/TTS is downstream of the search region's center, relative to the gene's strand.
A distance is positive if the TTS/TTS is upstream of the search region's center, relative to the gene's strand.

A transcript's location is always reported relative to the positive strand.

Image of Motifs and Modules

The image shown below illustrates the location of the motifs and modules within this search region.
However, the number of modules in a region may exceed the genome browser's track limit. Thus, for each type of module (pattern), the text in the yellow box below indicates whether or not any modules of that type exist, and if so, whether or not all the modules of that type are displayed. (If it indicates that only the top 20 modules are displayed, this ranking is based on the number of instances of each module.)

User-specified filter settings do not affect the features displayed in the UCSC genome browser view.

About the patterns shown in this image:
There are no 'de novo' patterns to show.
There are no (TRANSFAC) annotation-based patterns to show.
There are no (JASPAR) annotation-based patterns to show.

UCSC Genome Browser Image
Click on the image to view this region at UCSC.
    This image uses the C.elegans genome assembly from Jan 2007. (UCSC ce4, WS170, Ensembl v45) and contains a number of custom tracks followed by several UCSC tracks. The custom tracks show:
  • The long red and gray bar at the top shows the nominal 'search region' within which comparative genomics discovery methods were applied. Motif predictions were not made in coding exons and most types of repeats. In this database, the locations of masks applied to the search region are shown in gray.
  • The numbered brown blocks are 'atomic' motifs, i.e. conserved DNA sequence motifs that were identified by discovery methods and post-processing operations. Motifs are shaded to indicate the discovery p-value; a darker motif was more significant at the discovery stage.
  • Following the motif discovery stage, motifs were filtered by membership in co-occurring patterns, and patterns were ranked by genome-scale properties. Motifs instances that occur in highly-ranked putative regulatory modules may be more reliable predictions of functional genomic elements.
  • The connected sets of blue boxes are co-occurring patterns, i.e. putative regulatory modules. Modules are shaded to indicate the number of times that a pattern is found in the target genome; a darker module is associated with more search regions. An pattern is called either 'de novo' or annotation-based, depending on the type of groups that appear in the pattern. (see next point)
  • Before patterns (i.e. modules) can be identified from atomic motifs, groups of similar motifs must be found; modules are then identified as co-occurring 'group labels' that satisfy certain criteria. Such groups can be identified a) by annotating atomic motifs with known binding site resources from TRANSFAC, JASPAR or ORegAnno; or b) by 'de novo' clustering. Currently we show both types of patterns, but we consider annotation-based groups and patterns to be more reliable than 'de novo' groups and patterns. Work to improve genome-scale 'de novo' grouping is ongoing.

Motifs Found in this Region

The contents of the table below can be modified by changing your filter settings.
Currently, this table only contains motifs which:
+ have a discovery p-value < 1.0
+ were found using any of these algorithms: MotifSampler, Consensus.oops, Consensus.omops, Consensus.zmops, MEME.tcm, MEME.oops, MEME.zoops

Showing 32 out of 32 atomic motifs.

Group(s)
crtCele#(name) [p-value]
Motif
craCele#
Discovery
p-value
Location Width (+)motif (-)motif
0 annotated groups

0 'de novo' group(s)
273 4.39E-01 CHROMOSOME_II:9,522,601-9,522,614 14  Seq Logo
CTCTyyTnwCTTTG
Seq Logo
CAAAGsnArrAGAG
0 annotated groups

0 'de novo' group(s)
274 6.73E-01 CHROMOSOME_II:9,522,629-9,522,634 6  Seq Logo
AAGTAG
Seq Logo
CTACTT
0 annotated groups

0 'de novo' group(s)
275 6.40E-01 CHROMOSOME_II:9,522,654-9,522,665 12  Seq Logo
TTTTnAArCAGA
Seq Logo
TCTGyTTnAAAA
3 annotated group(s):
50025 (E4BP4) [2.02E-05]
50014 (Bsap) [4.15E-05]
50043 (HLF) [5.24E-05]

1 'de novo' group(s)
1876
276 6.66E-01 CHROMOSOME_II:9,522,675-9,522,691 17  Seq Logo
TnnATTACTTCAyTTTT
Seq Logo
AAAArTGAAGTAATnnA
0 annotated groups

0 'de novo' group(s)
277 7.91E-01 CHROMOSOME_II:9,522,769-9,522,788 20  Seq Logo
nwTTACTTCwCTTTTnnTTn
Seq Logo
nAAnnAAAAGsGAAGTAAsn
0 annotated groups

0 'de novo' group(s)
278 1.40E-01 CHROMOSOME_II:9,522,792-9,522,799 8  Seq Logo
AAGAATTA
Seq Logo
TAATTCTT
0 annotated groups

0 'de novo' group(s)
279 9.08E-01 CHROMOSOME_II:9,522,796-9,522,805 10  Seq Logo
ATAACATATC
Seq Logo
GATATGTTAT
0 annotated groups

0 'de novo' group(s)
280 1.00E-08 CHROMOSOME_II:9,522,848-9,522,853 6  Seq Logo
TGTTTC
Seq Logo
GAAACA
0 annotated groups

0 'de novo' group(s)
281 5.50E-01 CHROMOSOME_II:9,522,859-9,522,870 12  Seq Logo
TACkrTwTACGT
Seq Logo
ACGTAsAymGTA
0 annotated groups

1 'de novo' group(s)
94
282 5.38E-01 CHROMOSOME_II:9,522,867-9,522,877 11  Seq Logo
rnGTACTGTAn
Seq Logo
nTACAGTACny
0 annotated groups

0 'de novo' group(s)
283 5.15E-01 CHROMOSOME_II:9,523,074-9,523,083 10  Seq Logo
TTwTmAGnTT
Seq Logo
AAnCTkAsAA
1 annotated group(s):
40154 (Pax-5) [7.20E-06]

0 'de novo' group(s)
284 9.23E-01 CHROMOSOME_II:9,523,145-9,523,156 12  Seq Logo
CAGTCAAGATCA
Seq Logo
TGATCTTGACTG
1 annotated group(s):
40164 (POU2F1) [5.60E-06]

0 'de novo' group(s)
285 8.40E-02 CHROMOSOME_II:9,523,165-9,523,172 8  Seq Logo
TTwATGCA
Seq Logo
TGCATsAA
0 annotated groups

0 'de novo' group(s)
286 5.14E-01 CHROMOSOME_II:9,523,269-9,523,278 10  Seq Logo
GTAATTCGyn
Seq Logo
nrCGAATTAC
0 annotated groups

0 'de novo' group(s)
287 3.16E-01 CHROMOSOME_II:9,523,339-9,523,348 10  Seq Logo
TTTmGCTGmA
Seq Logo
TkCAGCkAAA
0 annotated groups

0 'de novo' group(s)
288 9.23E-01 CHROMOSOME_II:9,523,399-9,523,410 12  Seq Logo
TGATCTTGACTG
Seq Logo
CAGTCAAGATCA
0 annotated groups

0 'de novo' group(s)
289 8.20E-02 CHROMOSOME_II:9,523,438-9,523,445 8  Seq Logo
ATTCnTTG
Seq Logo
CAAnGAAT
0 annotated groups

0 'de novo' group(s)
290 2.67E-01 CHROMOSOME_II:9,523,459-9,523,475 17  Seq Logo
CAAArAATGAAGTAATA
Seq Logo
TATTACTTCATTyTTTG
0 annotated groups

0 'de novo' group(s)
291 5.76E-01 CHROMOSOME_II:9,523,476-9,523,490 15  Seq Logo
AwTTwCwTyATTTTT
Seq Logo
AAAAATrAsGsAAsT
0 annotated groups

2 'de novo' group(s)
94, 596
292 6.27E-01 CHROMOSOME_II:9,523,583-9,523,593 11  Seq Logo
TACAGTAmyyn
Seq Logo
nrrkTACTGTA
0 annotated groups

0 'de novo' group(s)
293 3.12E-01 CHROMOSOME_II:9,523,611-9,523,620 10  Seq Logo
AAGGmGCrTA
Seq Logo
TAyGCkCCTT
0 annotated groups

4 'de novo' group(s)
6, 675, 2773, 1570
295 6.74E-01 CHROMOSOME_II:9,523,638-9,523,661 24  Seq Logo
nGTCTCGCnACGnnTAC...
Seq Logo
GrnTACkGTAnnCGTnG...
0 annotated groups

1 'de novo' group(s)
2773
294 9.31E-01 CHROMOSOME_II:9,523,643-9,523,656 14  Seq Logo
CnCCACGAATACCG
Seq Logo
CGGTATTCGTGGnG
1 annotated group(s):
40138 (Nkx2-1) [4.55E-06]

1 'de novo' group(s)
363
296 8.74E-01 CHROMOSOME_II:9,523,666-9,523,673 8  Seq Logo
GGTAAATC
Seq Logo
GATTTACC
0 annotated groups

3 'de novo' group(s)
38, 591, 2007
297 9.68E-01 CHROMOSOME_II:9,523,693-9,523,704 12  Seq Logo
GACCGCCGGCGC
Seq Logo
GCGCCGGCGGTC
0 annotated groups

0 'de novo' group(s)
298 1.92E-01 CHROMOSOME_II:9,523,823-9,523,834 12  Seq Logo
TCTGCyTnAAAA
Seq Logo
TTTTnArGCAGA
0 annotated groups

0 'de novo' group(s)
299 7.98E-01 CHROMOSOME_II:9,523,923-9,523,940 18  Seq Logo
GTwCATTAATTArnCnsA
Seq Logo
TwnGnyTAATTAATGsAC
0 annotated groups

0 'de novo' group(s)
300 1.00E-08 CHROMOSOME_II:9,523,964-9,523,969 6  Seq Logo
CAGCTA
Seq Logo
TAGCTG
0 annotated groups

0 'de novo' group(s)
301 5.49E-01 CHROMOSOME_II:9,524,011-9,524,022 12  Seq Logo
CnTCCTGCATkA
Seq Logo
TmATGCAGGAnG
0 annotated groups

0 'de novo' group(s)
302 1.00E-08 CHROMOSOME_II:9,524,021-9,524,026 6  Seq Logo
GAAACA
Seq Logo
TGTTTC
0 annotated groups

0 'de novo' group(s)
303 6.95E-01 CHROMOSOME_II:9,524,033-9,524,044 12  Seq Logo
wTTTkACTGnGT
Seq Logo
ACnCAGTmAAAs
0 annotated groups

0 'de novo' group(s)
304 2.99E-01 CHROMOSOME_II:9,524,082-9,524,093 12  Seq Logo
TTTTnArrCAGA
Seq Logo
TCTGyyTnAAAA

Questions or comments: cisred@bcgsc.ca