FILTERS:
pvalue:1.0
Region for Gene B0041.3
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This page describes one promoter-based search region.

Page Contents

Overview
Genomic Context
Image of Motifs and Modules
Motifs Found in this Region
Search region overview
Search region location CHROMOSOME_I:4,644,056-4,644,680 (+) (625 bp)
Assembly C.elegans, Ensembl v45 (WS170)
WormBase ID B0041.3
Modules
(Co-occurring motif patterns)
No annotation-based modules were found.
No 'de novo' modules exist in this database.

Genomic Context: C.elegans genome assembly from Jan 2007. (UCSC ce4, WS170, Ensembl v45)

The image shown below was created to provide context for this search region by showing a 100000 bp span of the genome, centered on this search region.

UCSC Genome Browser Image    
  • The first track shows the location of the search region in red.
  • The last track shows known gene locations in this 100000 bp span of the genome.

This promoter-based search region is located close to a particular gene of interest, described in the table below. Click on the gene id to open a page at ensembl.org with more information about this gene.

Target gene used to create this search region
WormBase ID B0041.3
Gene location CHROMOSOME_I: 4,644,681-4,645,626 (+) (946 bp)
Distance from the region's midpoint to TSS -311
The distance from a cisred search region to a gene, is measured from the center of the search region to either the transcription termination site (TTS) or the transcription start site (TSS), whichever is closer.
A distance is negative if the TTS/TTS is downstream of the search region's center, relative to the gene's strand.
A distance is positive if the TTS/TTS is upstream of the search region's center, relative to the gene's strand.

A transcript's location is always reported relative to the positive strand.

Image of Motifs and Modules

The image shown below illustrates the location of the motifs and modules within this search region.
However, the number of modules in a region may exceed the genome browser's track limit. Thus, for each type of module (pattern), the text in the yellow box below indicates whether or not any modules of that type exist, and if so, whether or not all the modules of that type are displayed. (If it indicates that only the top 20 modules are displayed, this ranking is based on the number of instances of each module.)

User-specified filter settings do not affect the features displayed in the UCSC genome browser view.

About the patterns shown in this image:
There are no 'de novo' patterns to show.
There are no (TRANSFAC) annotation-based patterns to show.
There are no (JASPAR) annotation-based patterns to show.

UCSC Genome Browser Image
Click on the image to view this region at UCSC.
    This image uses the C.elegans genome assembly from Jan 2007. (UCSC ce4, WS170, Ensembl v45) and contains a number of custom tracks followed by several UCSC tracks. The custom tracks show:
  • The long red and gray bar at the top shows the nominal 'search region' within which comparative genomics discovery methods were applied. Motif predictions were not made in coding exons and most types of repeats. In this database, the locations of masks applied to the search region are shown in gray.
  • The numbered brown blocks are 'atomic' motifs, i.e. conserved DNA sequence motifs that were identified by discovery methods and post-processing operations. Motifs are shaded to indicate the discovery p-value; a darker motif was more significant at the discovery stage.
  • Following the motif discovery stage, motifs were filtered by membership in co-occurring patterns, and patterns were ranked by genome-scale properties. Motifs instances that occur in highly-ranked putative regulatory modules may be more reliable predictions of functional genomic elements.
  • The connected sets of blue boxes are co-occurring patterns, i.e. putative regulatory modules. Modules are shaded to indicate the number of times that a pattern is found in the target genome; a darker module is associated with more search regions. An pattern is called either 'de novo' or annotation-based, depending on the type of groups that appear in the pattern. (see next point)
  • Before patterns (i.e. modules) can be identified from atomic motifs, groups of similar motifs must be found; modules are then identified as co-occurring 'group labels' that satisfy certain criteria. Such groups can be identified a) by annotating atomic motifs with known binding site resources from TRANSFAC, JASPAR or ORegAnno; or b) by 'de novo' clustering. Currently we show both types of patterns, but we consider annotation-based groups and patterns to be more reliable than 'de novo' groups and patterns. Work to improve genome-scale 'de novo' grouping is ongoing.

Motifs Found in this Region

The contents of the table below can be modified by changing your filter settings.
Currently, this table only contains motifs which:
+ have a discovery p-value < 1.0
+ were found using any of these algorithms: MotifSampler, Consensus.oops, Consensus.omops, Consensus.zmops, MEME.tcm, MEME.oops, MEME.zoops

Showing 42 out of 42 atomic motifs.

Group(s)
crtCele#(name) [p-value]
Motif
craCele#
Discovery
p-value
Location Width (+)motif (-)motif
0 annotated groups

0 'de novo' group(s)
1212 8.22E-01 CHROMOSOME_I:4,644,059-4,644,068 10  Seq Logo
TGTTTGCACy
Seq Logo
rGTGCAAACA
0 annotated groups

2 'de novo' group(s)
59, 278
1211 9.54E-01 CHROMOSOME_I:4,644,061-4,644,072 12  Seq Logo
kTyGAACCmyGw
Seq Logo
sCrkGGTTCrAm
0 annotated groups

0 'de novo' group(s)
1213 9.19E-01 CHROMOSOME_I:4,644,067-4,644,076 10  Seq Logo
AmCCCTGAAA
Seq Logo
TTTCAGGGkT
5 annotated group(s):
50029 (Evi-1) [1.27E-06]
40073 (Evi-1) [2.02E-06]
40073 (Evi-1) [3.03E-06]
...


2 'de novo' group(s)
1, 604
1214 6.62E-01 CHROMOSOME_I:4,644,078-4,644,093 16  Seq Logo
nACTTATCTTATCnTT
Seq Logo
AAnGATAAGATAAGTn
1 annotated group(s):
30010 (ELT-2) [1.12E-04]

1 'de novo' group(s)
1
1215 8.22E-01 CHROMOSOME_I:4,644,121-4,644,130 10  Seq Logo
GATAAGwTnA
Seq Logo
TnAsCTTATC
0 annotated groups

0 'de novo' group(s)
1216 8.32E-01 CHROMOSOME_I:4,644,136-4,644,153 18  Seq Logo
AAGGmAkAkAAwAAArns
Seq Logo
wnyTTTsTTmTmTkCCTT
1 annotated group(s):
50047 (HNF-3beta) [8.05E-05]

0 'de novo' group(s)
1221 7.01E-01 CHROMOSOME_I:4,644,160-4,644,173 14  Seq Logo
TTTTTmTmTGCCTT
Seq Logo
AAGGCAkAkAAAAA
1 annotated group(s):
50047 (HNF-3beta) [8.05E-05]

0 'de novo' group(s)
1217 7.57E-01 CHROMOSOME_I:4,644,164-4,644,175 12  Seq Logo
TTTTTGsTTTAA
Seq Logo
TTAAAwCAAAAA
1 annotated group(s):
50047 (HNF-3beta) [8.05E-05]

0 'de novo' group(s)
1219 8.40E-01 CHROMOSOME_I:4,644,167-4,644,176 10  Seq Logo
wTGsTTTAAm
Seq Logo
kTTAAAwCAs
0 annotated groups

0 'de novo' group(s)
1222 3.16E-01 CHROMOSOME_I:4,644,178-4,644,183 6  Seq Logo
TATATT
Seq Logo
AATATA
1 annotated group(s):
50101 (c-REL) [5.63E-05]

0 'de novo' group(s)
1223 9.08E-01 CHROMOSOME_I:4,644,214-4,644,231 18  Seq Logo
ynynnTTTyTCCTTTTTy
Seq Logo
rAAAAAGGArAAAnnrnr
0 annotated groups

0 'de novo' group(s)
1224 2.26E-01 CHROMOSOME_I:4,644,265-4,644,272 8  Seq Logo
ArrCAAAT
Seq Logo
ATTTGyyT
1 annotated group(s):
50070 (Pbx) [2.50E-05]

0 'de novo' group(s)
1225 9.55E-01 CHROMOSOME_I:4,644,304-4,644,317 14  Seq Logo
AnTwnTCGrTAATk
Seq Logo
mATTAyCGAnsAnT
0 annotated groups

0 'de novo' group(s)
1226 6.90E-01 CHROMOSOME_I:4,644,316-4,644,323 8  Seq Logo
TkTyTGCr
Seq Logo
yGCArAmA
0 annotated groups

0 'de novo' group(s)
1227 9.08E-01 CHROMOSOME_I:4,644,326-4,644,333 8  Seq Logo
wTATATGC
Seq Logo
GCATATAs
0 annotated groups

0 'de novo' group(s)
1228 3.52E-01 CHROMOSOME_I:4,644,331-4,644,338 8  Seq Logo
yGCAAAmA
Seq Logo
TkTTTGCr
0 annotated groups

0 'de novo' group(s)
1229 9.89E-01 CHROMOSOME_I:4,644,337-4,644,360 24  Seq Logo
AAGrCAkAkAAAAAArA...
Seq Logo
TsCAynkTyTTTTTTmT...
0 annotated groups

2 'de novo' group(s)
2850, 2075
1231 9.93E-01 CHROMOSOME_I:4,644,364-4,644,383 20  Seq Logo
AGTGCAAACAnAAnAAmnGA
Seq Logo
TCnkTTnTTnTGTTTGCACT
0 annotated groups

0 'de novo' group(s)
1230 9.10E-01 CHROMOSOME_I:4,644,365-4,644,376 12  Seq Logo
GTknAAmCATrA
Seq Logo
TyATGkTTnmAC
1 annotated group(s):
40034 (CAC-binding_protein) [5.80E-06]

4 'de novo' group(s)
4, 33, 43, 674
1233 9.50E-01 CHROMOSOME_I:4,644,380-4,644,403 24  Seq Logo
AwnACrCsCGATyrmkT...
Seq Logo
nnAwnwGAmkyrATCGw...
0 annotated groups

1 'de novo' group(s)
43
1232 9.86E-01 CHROMOSOME_I:4,644,381-4,644,390 10  Seq Logo
TGACnCCTGA
Seq Logo
TCAGGnGTCA
0 annotated groups

0 'de novo' group(s)
1234 7.42E-01 CHROMOSOME_I:4,644,405-4,644,414 10  Seq Logo
CCACTTCTCC
Seq Logo
GGAGAAGTGG
2 annotated group(s):
40147 (NRSF) [7.59E-06]
50014 (Bsap) [4.62E-05]

0 'de novo' group(s)
1235 8.49E-01 CHROMOSOME_I:4,644,417-4,644,438 22  Seq Logo
yTmTTTsGCATATTyyC...
Seq Logo
mrwAAGrrAATATGCwA...
3 annotated group(s):
40147 (NRSF) [7.59E-06]
40154 (Pax-5) [8.32E-06]
50014 (Bsap) [4.62E-05]

2 'de novo' group(s)
63, 77
1236 9.28E-01 CHROMOSOME_I:4,644,434-4,644,450 17  Seq Logo
TTCyGCGCCTGGGCCnm
Seq Logo
knGGCCCAGGCGCrGAA
3 annotated group(s):
40154 (Pax-5) [8.32E-06]
50048 (Hen-1) [4.55E-05]
50014 (Bsap) [6.21E-05]

1 'de novo' group(s)
22
1237 6.00E-01 CHROMOSOME_I:4,644,449-4,644,469 21  Seq Logo
ymCAsCCGAATTGATCG...
Seq Logo
CAyGCGATCAATTCGGw...
0 annotated groups

1 'de novo' group(s)
49
1238 9.53E-01 CHROMOSOME_I:4,644,479-4,644,488 10  Seq Logo
CCAGyGArAG
Seq Logo
CTyTCrCTGG
0 annotated groups

0 'de novo' group(s)
1239 6.75E-01 CHROMOSOME_I:4,644,489-4,644,495 7  Seq Logo
wGTGTAT
Seq Logo
ATACACs
0 annotated groups

0 'de novo' group(s)
1240 2.56E-01 CHROMOSOME_I:4,644,499-4,644,506 8  Seq Logo
TCyCTTTT
Seq Logo
AAAAGrGA
0 annotated groups

0 'de novo' group(s)
1241 6.60E-01 CHROMOSOME_I:4,644,508-4,644,525 18  Seq Logo
yknmCwTTTCTCCTTTTy
Seq Logo
rAAAAGGAGAAAsGknmr
0 annotated groups

0 'de novo' group(s)
1242 8.37E-01 CHROMOSOME_I:4,644,529-4,644,540 12  Seq Logo
ynTCTCCTynTy
Seq Logo
rAnrAGGAGAnr
0 annotated groups

0 'de novo' group(s)
1243 8.49E-01 CHROMOSOME_I:4,644,539-4,644,554 16  Seq Logo
wwGTGwwTTAnwAwAw
Seq Logo
sTsTsnTAAssCACss
0 annotated groups

0 'de novo' group(s)
1244 4.40E-01 CHROMOSOME_I:4,644,563-4,644,572 10  Seq Logo
TArAwCAsTw
Seq Logo
sAwTGsTyTA
0 annotated groups

0 'de novo' group(s)
1245 9.39E-01 CHROMOSOME_I:4,644,572-4,644,587 16  Seq Logo
TTnTATAAATATAnGn
Seq Logo
nCnTATATTTATAnAA
0 annotated groups

0 'de novo' group(s)
1246 9.53E-01 CHROMOSOME_I:4,644,616-4,644,626 11  Seq Logo
nTTAAACCATr
Seq Logo
yATGGTTTAAn
0 annotated groups

0 'de novo' group(s)
1247 9.08E-01 CHROMOSOME_I:4,644,617-4,644,624 8  Seq Logo
TTAAACCA
Seq Logo
TGGTTTAA
0 annotated groups

0 'de novo' group(s)
1249 9.96E-01 CHROMOSOME_I:4,644,617-4,644,628 12  Seq Logo
TTrAAsmATAAw
Seq Logo
sTTATkwTTyAA
0 annotated groups

0 'de novo' group(s)
1250 9.97E-01 CHROMOSOME_I:4,644,619-4,644,632 14  Seq Logo
nGATAAGATwAkTn
Seq Logo
nAmTsATCTTATCn
0 annotated groups

1 'de novo' group(s)
12
1251 9.94E-01 CHROMOSOME_I:4,644,631-4,644,644 14  Seq Logo
TTwAAACCATrAAT
Seq Logo
ATTyATGGTTTsAA
0 annotated groups

0 'de novo' group(s)
1252 5.38E-01 CHROMOSOME_I:4,644,636-4,644,646 11  Seq Logo
GCGATCAwTTC
Seq Logo
GAAsTGATCGC
0 annotated groups

0 'de novo' group(s)
1253 5.26E-01 CHROMOSOME_I:4,644,646-4,644,661 16  Seq Logo
CArTrAAAAmGGAGAr
Seq Logo
yTCTCCkTTTTyAyTG
0 annotated groups

0 'de novo' group(s)
1254 7.95E-01 CHROMOSOME_I:4,644,659-4,644,668 10  Seq Logo
GAACsAyGAw
Seq Logo
sTCrTwGTTC
1 annotated group(s):
50069 (Pax6) [3.90E-05]

0 'de novo' group(s)
1255 3.63E-01 CHROMOSOME_I:4,644,666-4,644,679 14  Seq Logo
GTTrAACCATGAAT
Seq Logo
ATTCATGGTTyAAC

Questions or comments: cisred@bcgsc.ca