FILTERS:
pvalue:0.25
Region for Gene ENSRNOG00000000109 (RefSeq: NM_023961)
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This page describes one promoter-based search region.

Page Contents

Overview
Genomic Context
Image of Motifs and Modules
Motifs Found in this Region
Search region overview
Search region location chr16:55,385,298-55,387,023 (+) (1726 bp)
Assembly Rat, Ensembl v22 (RGSC 3.1)
Gene name NM_023961
Ensembl gene ID ENSRNOG00000000109
Gene description source RefSeq
Modules
(Co-occurring motif patterns)
No annotation-based modules were found.
1 'de novo' module(s)

Genomic Context: Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22)

The image shown below was created to provide context for this search region by showing a 100000 bp span of the genome, centered on this search region.

UCSC Genome Browser Image    
  • The first track shows the location of the search region in red.
  • The last track shows known gene locations in this 100000 bp span of the genome.

This promoter-based search region is located close to a particular gene of interest, described in the table below. Click on the gene id to open a page at ensembl.org with more information about this gene.

Target gene used to create this search region
Ensembl ID ENSRNOG00000000109 (NM_023961)
Ensembl Transcript ID ENSRNOT00000000121
Gene location chr16: 55,387,062-55,393,819 (+) (6,758 bp)
Distance from the region's midpoint to TSS -900
The distance from a cisred search region to a gene, is measured from the center of the search region to either the transcription termination site (TTS) or the transcription start site (TSS), whichever is closer.
A distance is negative if the TTS/TTS is downstream of the search region's center, relative to the gene's strand.
A distance is positive if the TTS/TTS is upstream of the search region's center, relative to the gene's strand.

A transcript's location is always reported relative to the positive strand.

Image of Motifs and Modules

The image shown below illustrates the location of the motifs and modules within this search region.
However, the number of modules in a region may exceed the genome browser's track limit. Thus, for each type of module (pattern), the text in the yellow box below indicates whether or not any modules of that type exist, and if so, whether or not all the modules of that type are displayed. (If it indicates that only the top 20 modules are displayed, this ranking is based on the number of instances of each module.)

User-specified filter settings do not affect the features displayed in the UCSC genome browser view.

About the patterns shown in this image:
There are no 'de novo' patterns to show.
There are no (TRANSFAC) annotation-based patterns to show.
There are no (JASPAR) annotation-based patterns to show.

UCSC Genome Browser Image
Click on the image to view this region at UCSC.
    This image uses the Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22) and contains a number of custom tracks followed by several UCSC tracks. The custom tracks show:
  • The long red and gray bar at the top shows the nominal 'search region' within which comparative genomics discovery methods were applied. Motif predictions were not made in coding exons and most types of repeats. In this database, the locations of masks applied to the search region are shown in gray.
  • The numbered brown blocks are 'atomic' motifs, i.e. conserved DNA sequence motifs that were identified by discovery methods and post-processing operations. Motifs are shaded to indicate the discovery p-value; a darker motif was more significant at the discovery stage.
  • Following the motif discovery stage, motifs were filtered by membership in co-occurring patterns, and patterns were ranked by genome-scale properties. Motifs instances that occur in highly-ranked putative regulatory modules may be more reliable predictions of functional genomic elements.
  • The connected sets of blue boxes are co-occurring patterns, i.e. putative regulatory modules. Modules are shaded to indicate the number of times that a pattern is found in the target genome; a darker module is associated with more search regions. An pattern is called either 'de novo' or annotation-based, depending on the type of groups that appear in the pattern. (see next point)
  • Before patterns (i.e. modules) can be identified from atomic motifs, groups of similar motifs must be found; modules are then identified as co-occurring 'group labels' that satisfy certain criteria. Such groups can be identified a) by annotating atomic motifs with known binding site resources from TRANSFAC, JASPAR or ORegAnno; or b) by 'de novo' clustering. Currently we show both types of patterns, but we consider annotation-based groups and patterns to be more reliable than 'de novo' groups and patterns. Work to improve genome-scale 'de novo' grouping is ongoing.

Motifs Found in this Region

The contents of the table below can be modified by changing your filter settings.
Currently, this table only contains motifs which:
+ have a discovery p-value < 0.25
+ were found using any of these algorithms: MotifSampler, Consensus.oops, Consensus.omops, Consensus.zmops, MEME.tcm, MEME.oops, MEME.zoops

Showing 13 out of 13 atomic motifs.

Group(s)
crtRnor#(name) [p-value]
Motif
craRnor#
Discovery
p-value
Location Width (+)motif (-)motif
0 annotated groups

1 'de novo' group(s)
14867
2133 7.37E-02 chr16:55,386,506-55,386,529 24  Seq Logo
AGsrCTTnATTArCATA...
Seq Logo
CyTGAyATATGyTAATn...
0 annotated groups

1 'de novo' group(s)
5132
2066 2.32E-01 chr16:55,386,512-55,386,517 6  Seq Logo
ATAGAT
Seq Logo
ATCTAT
0 annotated groups

1 'de novo' group(s)
5132
2098 2.32E-01 chr16:55,386,518-55,386,523 6  Seq Logo
ATCTAT
Seq Logo
ATAGAT
0 annotated groups

0 'de novo' group(s)
2175 7.76E-02 chr16:55,386,626-55,386,640 15  Seq Logo
ACCmGCATATATAsy
Seq Logo
rwTATATATGCkGGT
0 annotated groups

1 'de novo' group(s)
14987
2251 1.05E-01 chr16:55,386,648-55,386,668 21  Seq Logo
CTTTTATCATTTAGATG...
Seq Logo
CCCCCATCTAAATGATA...
0 annotated groups

1 'de novo' group(s)
9504
2341 7.54E-03 chr16:55,386,672-55,386,683 12  Seq Logo
ACCkCCCCGGCr
Seq Logo
yGCCGGGGmGGT
0 annotated groups

1 'de novo' group(s)
3259
2393 1.52E-01 chr16:55,386,681-55,386,686 6  Seq Logo
GCGCGC
Seq Logo
GCGCGC
0 annotated groups

1 'de novo' group(s)
15801
2428 8.33E-03 chr16:55,386,693-55,386,715 23  Seq Logo
GGACTTGATTAGCATAT...
Seq Logo
CTTGACATATGCTAATC...
0 annotated groups

0 'de novo' group(s)
2525 1.68E-01 chr16:55,386,722-55,386,735 14  Seq Logo
CGCATATATACTCG
Seq Logo
CGAGTATATATGCG
0 annotated groups

0 'de novo' group(s)
2632 1.16E-01 chr16:55,386,755-55,386,772 18  Seq Logo
AAGGACyTGATTAGCATA
Seq Logo
TATGCTAATCArGTCCTT
0 annotated groups

0 'de novo' group(s)
2713 1.14E-01 chr16:55,386,996-55,387,007 12  Seq Logo
TTAGAyTGTmwA
Seq Logo
TskACArTCTAA
0 annotated groups

1 'de novo' group(s)
5199
2773 5.49E-03 chr16:55,387,003-55,387,008 6  Seq Logo
TTTTAT
Seq Logo
ATAAAA
0 annotated groups

0 'de novo' group(s)
2855 7.46E-03 chr16:55,387,008-55,387,019 12  Seq Logo
kkGGGGGGrrnr
Seq Logo
ynyyCCCCCCmm

Questions or comments: cisred@bcgsc.ca