FILTERS:
pvalue:0.25
Region for Gene ENSRNOG00000000145 (RefSeq: NM_022213)
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This page describes one promoter-based search region.

Page Contents

Overview
Genomic Context
Image of Motifs and Modules
Motifs Found in this Region
Search region overview
Search region location chr5:136,500,796-136,502,527 (+) (1732 bp)
Assembly Rat, Ensembl v22 (RGSC 3.1)
Gene name NM_022213
Ensembl gene ID ENSRNOG00000000145
Gene description source RefSeq
Modules
(Co-occurring motif patterns)
No annotation-based modules were found.
No 'de novo' modules were found.

Genomic Context: Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22)

The image shown below was created to provide context for this search region by showing a 100000 bp span of the genome, centered on this search region.

UCSC Genome Browser Image    
  • The first track shows the location of the search region in red.
  • The last track shows known gene locations in this 100000 bp span of the genome.

This promoter-based search region is located close to a particular gene of interest, described in the table below. Click on the gene id to open a page at ensembl.org with more information about this gene.

Target gene used to create this search region
Ensembl ID ENSRNOG00000000145 (NM_022213)
Ensembl Transcript ID ENSRNOT00000000157
Gene location chr5: 136,502,720-136,571,699 (+) (68,980 bp)
Distance from the region's midpoint to TSS -1057
The distance from a cisred search region to a gene, is measured from the center of the search region to either the transcription termination site (TTS) or the transcription start site (TSS), whichever is closer.
A distance is negative if the TTS/TTS is downstream of the search region's center, relative to the gene's strand.
A distance is positive if the TTS/TTS is upstream of the search region's center, relative to the gene's strand.

A transcript's location is always reported relative to the positive strand.

Image of Motifs and Modules

The image shown below illustrates the location of the motifs and modules within this search region.
However, the number of modules in a region may exceed the genome browser's track limit. Thus, for each type of module (pattern), the text in the yellow box below indicates whether or not any modules of that type exist, and if so, whether or not all the modules of that type are displayed. (If it indicates that only the top 20 modules are displayed, this ranking is based on the number of instances of each module.)

User-specified filter settings do not affect the features displayed in the UCSC genome browser view.

About the patterns shown in this image:
There are no 'de novo' patterns to show.
There are no (TRANSFAC) annotation-based patterns to show.
There are no (JASPAR) annotation-based patterns to show.

UCSC Genome Browser Image
Click on the image to view this region at UCSC.
    This image uses the Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22) and contains a number of custom tracks followed by several UCSC tracks. The custom tracks show:
  • The long red and gray bar at the top shows the nominal 'search region' within which comparative genomics discovery methods were applied. Motif predictions were not made in coding exons and most types of repeats. In this database, the locations of masks applied to the search region are shown in gray.
  • The numbered brown blocks are 'atomic' motifs, i.e. conserved DNA sequence motifs that were identified by discovery methods and post-processing operations. Motifs are shaded to indicate the discovery p-value; a darker motif was more significant at the discovery stage.
  • Following the motif discovery stage, motifs were filtered by membership in co-occurring patterns, and patterns were ranked by genome-scale properties. Motifs instances that occur in highly-ranked putative regulatory modules may be more reliable predictions of functional genomic elements.
  • The connected sets of blue boxes are co-occurring patterns, i.e. putative regulatory modules. Modules are shaded to indicate the number of times that a pattern is found in the target genome; a darker module is associated with more search regions. An pattern is called either 'de novo' or annotation-based, depending on the type of groups that appear in the pattern. (see next point)
  • Before patterns (i.e. modules) can be identified from atomic motifs, groups of similar motifs must be found; modules are then identified as co-occurring 'group labels' that satisfy certain criteria. Such groups can be identified a) by annotating atomic motifs with known binding site resources from TRANSFAC, JASPAR or ORegAnno; or b) by 'de novo' clustering. Currently we show both types of patterns, but we consider annotation-based groups and patterns to be more reliable than 'de novo' groups and patterns. Work to improve genome-scale 'de novo' grouping is ongoing.

Motifs Found in this Region

The contents of the table below can be modified by changing your filter settings.
Currently, this table only contains motifs which:
+ have a discovery p-value < 0.25
+ were found using any of these algorithms: MotifSampler, Consensus.oops, Consensus.omops, Consensus.zmops, MEME.tcm, MEME.oops, MEME.zoops

Showing 24 out of 24 atomic motifs.

Group(s)
crtRnor#(name) [p-value]
Motif
craRnor#
Discovery
p-value
Location Width (+)motif (-)motif
0 annotated groups

1 'de novo' group(s)
5145
8655 1.56E-01 chr5:136,501,161-136,501,166 6  Seq Logo
ATTTAA
Seq Logo
TTAAAT
0 annotated groups

1 'de novo' group(s)
1112
8693 1.30E-01 chr5:136,501,298-136,501,307 10  Seq Logo
CGyCTCmCGC
Seq Logo
GCGkGAGrCG
0 annotated groups

1 'de novo' group(s)
12615
8751 6.36E-02 chr5:136,501,327-136,501,341 15  Seq Logo
GAGGCTCGGkCsnsC
Seq Logo
GwnwGmCCGAGCCTC
0 annotated groups

0 'de novo' group(s)
8795 5.14E-02 chr5:136,501,392-136,501,411 20  Seq Logo
CyCCCCCAGCCTCAATCAGA
Seq Logo
TCTGATTGAGGCTGGGGGrG
0 annotated groups

0 'de novo' group(s)
8830 2.20E-03 chr5:136,501,446-136,501,456 11  Seq Logo
AACCGCCGTTT
Seq Logo
AAACGGCGGTT
0 annotated groups

1 'de novo' group(s)
6744
8922 1.03E-01 chr5:136,501,447-136,501,452 6  Seq Logo
ACCGCC
Seq Logo
GGCGGT
0 annotated groups

1 'de novo' group(s)
5564
8950 5.49E-03 chr5:136,501,449-136,501,454 6  Seq Logo
CGCCGT
Seq Logo
ACGGCG
0 annotated groups

1 'de novo' group(s)
12656
9042 5.25E-02 chr5:136,501,559-136,501,576 18  Seq Logo
nnCCnGCCrGCGCCGGCT
Seq Logo
AGCCGGCGCyGGCnGGnn
0 annotated groups

1 'de novo' group(s)
14670
9074 5.09E-02 chr5:136,501,704-136,501,725 22  Seq Logo
TGGrGkGCsGCCAGCGC...
Seq Logo
kCCGGGCGCTGGCwGCm...
0 annotated groups

1 'de novo' group(s)
15871
9153 5.17E-02 chr5:136,501,736-136,501,764 29  Seq Logo
GAAGGAGCGGGAGACss...
Seq Logo
TGGGGCGCGCAGwwGTC...
0 annotated groups

0 'de novo' group(s)
9119 2.37E-01 chr5:136,501,753-136,501,760 8  Seq Logo
CGrACTGT
Seq Logo
ACAGTyCG
0 annotated groups

1 'de novo' group(s)
5103
9212 1.61E-01 chr5:136,501,836-136,501,841 6  Seq Logo
TTAAAA
Seq Logo
TTTTAA
0 annotated groups

1 'de novo' group(s)
12676
9256 5.13E-02 chr5:136,501,840-136,501,854 15  Seq Logo
TGrTTGAGGCkGGGG
Seq Logo
CCCCmGCCTCAAyCA
0 annotated groups

0 'de novo' group(s)
9311 2.02E-01 chr5:136,501,968-136,501,984 17  Seq Logo
GGCGCCTCAGCGGGGGn
Seq Logo
nCCCCCGCTGAGGCGCC
0 annotated groups

1 'de novo' group(s)
13537
9347 5.11E-02 chr5:136,501,989-136,502,009 21  Seq Logo
GCGnsksAGCGGGGGAG...
Seq Logo
CACwCTCCCCCGCTwmw...
0 annotated groups

1 'de novo' group(s)
11260
9369 1.03E-02 chr5:136,502,023-136,502,036 14  Seq Logo
sTTAAAATGAAACT
Seq Logo
AGTTTCATTTTAAw
0 annotated groups

0 'de novo' group(s)
9447 5.13E-02 chr5:136,502,051-136,502,082 32  Seq Logo
GCTCCwGCrrAGGAGCG...
Seq Logo
CGCGCAGCCGTCTCCCG...
0 annotated groups

0 'de novo' group(s)
9406 5.45E-02 chr5:136,502,059-136,502,068 10  Seq Logo
AGCGGGAGsC
Seq Logo
GwCTCCCGCT
0 annotated groups

1 'de novo' group(s)
6029
9509 1.57E-01 chr5:136,502,133-136,502,145 13  Seq Logo
GGGACACCCTCCC
Seq Logo
GGGAGGGTGTCCC
0 annotated groups

1 'de novo' group(s)
6029
9596 2.29E-01 chr5:136,502,134-136,502,145 12  Seq Logo
GGACrCCmTCCC
Seq Logo
GGGAkGGyGTCC
0 annotated groups

0 'de novo' group(s)
9648 1.53E-01 chr5:136,502,135-136,502,146 12  Seq Logo
GTCsCCCTCCGC
Seq Logo
GCGGAGGGwGAC
0 annotated groups

0 'de novo' group(s)
9686 5.12E-02 chr5:136,502,221-136,502,258 38  Seq Logo
GCAGACCAGTGGGACCC...
Seq Logo
GGnGnTTGCGTTCAAGT...
0 annotated groups

1 'de novo' group(s)
10129
9722 6.42E-02 chr5:136,502,295-136,502,304 10  Seq Logo
AACGCGwTCT
Seq Logo
AGAsCGCGTT
0 annotated groups

1 'de novo' group(s)
5103
9760 1.61E-01 chr5:136,502,438-136,502,443 6  Seq Logo
TTTTAA
Seq Logo
TTAAAA

Questions or comments: cisred@bcgsc.ca