FILTERS:
pvalue:0.25
Region for Gene ENSRNOG00000000805 (Uniprot/SWISSPROT: Gja1)
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This page describes one promoter-based search region.

Page Contents

Overview
Genomic Context
Image of Motifs and Modules
Motifs Found in this Region
Search region overview
Search region location chr20:35,421,442-35,423,806 (+) (2365 bp)
Assembly Rat, Ensembl v22 (RGSC 3.1)
Gene name Gja1
Ensembl gene ID ENSRNOG00000000805
Gene description source Uniprot/SWISSPROT
Modules
(Co-occurring motif patterns)
No annotation-based modules were found.
No 'de novo' modules were found.

Genomic Context: Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22)

The image shown below was created to provide context for this search region by showing a 100000 bp span of the genome, centered on this search region.

UCSC Genome Browser Image    
  • The first track shows the location of the search region in red.
  • The last track shows known gene locations in this 100000 bp span of the genome.

This promoter-based search region is located close to a particular gene of interest, described in the table below. Click on the gene id to open a page at ensembl.org with more information about this gene.

Target gene used to create this search region
Ensembl ID ENSRNOG00000000805 (Gja1)
Ensembl Transcript ID ENSRNOT00000001054
Gene location chr20: 35,423,615-35,436,064 (+) (12,450 bp)
Distance from the region's midpoint to TSS -989
The distance from a cisred search region to a gene, is measured from the center of the search region to either the transcription termination site (TTS) or the transcription start site (TSS), whichever is closer.
A distance is negative if the TTS/TTS is downstream of the search region's center, relative to the gene's strand.
A distance is positive if the TTS/TTS is upstream of the search region's center, relative to the gene's strand.

A transcript's location is always reported relative to the positive strand.

Image of Motifs and Modules

The image shown below illustrates the location of the motifs and modules within this search region.
However, the number of modules in a region may exceed the genome browser's track limit. Thus, for each type of module (pattern), the text in the yellow box below indicates whether or not any modules of that type exist, and if so, whether or not all the modules of that type are displayed. (If it indicates that only the top 20 modules are displayed, this ranking is based on the number of instances of each module.)

User-specified filter settings do not affect the features displayed in the UCSC genome browser view.

About the patterns shown in this image:
There are no 'de novo' patterns to show.
There are no (TRANSFAC) annotation-based patterns to show.
There are no (JASPAR) annotation-based patterns to show.

UCSC Genome Browser Image
Click on the image to view this region at UCSC.
    This image uses the Rat genome assembly from Jun 2003. (UCSC rn3, RGSC 3.1, Ensembl v22) and contains a number of custom tracks followed by several UCSC tracks. The custom tracks show:
  • The long red and gray bar at the top shows the nominal 'search region' within which comparative genomics discovery methods were applied. Motif predictions were not made in coding exons and most types of repeats. In this database, the locations of masks applied to the search region are shown in gray.
  • The numbered brown blocks are 'atomic' motifs, i.e. conserved DNA sequence motifs that were identified by discovery methods and post-processing operations. Motifs are shaded to indicate the discovery p-value; a darker motif was more significant at the discovery stage.
  • Following the motif discovery stage, motifs were filtered by membership in co-occurring patterns, and patterns were ranked by genome-scale properties. Motifs instances that occur in highly-ranked putative regulatory modules may be more reliable predictions of functional genomic elements.
  • The connected sets of blue boxes are co-occurring patterns, i.e. putative regulatory modules. Modules are shaded to indicate the number of times that a pattern is found in the target genome; a darker module is associated with more search regions. An pattern is called either 'de novo' or annotation-based, depending on the type of groups that appear in the pattern. (see next point)
  • Before patterns (i.e. modules) can be identified from atomic motifs, groups of similar motifs must be found; modules are then identified as co-occurring 'group labels' that satisfy certain criteria. Such groups can be identified a) by annotating atomic motifs with known binding site resources from TRANSFAC, JASPAR or ORegAnno; or b) by 'de novo' clustering. Currently we show both types of patterns, but we consider annotation-based groups and patterns to be more reliable than 'de novo' groups and patterns. Work to improve genome-scale 'de novo' grouping is ongoing.

Motifs Found in this Region

The contents of the table below can be modified by changing your filter settings.
Currently, this table only contains motifs which:
+ have a discovery p-value < 0.25
+ were found using any of these algorithms: MotifSampler, Consensus.oops, Consensus.omops, Consensus.zmops, MEME.tcm, MEME.oops, MEME.zoops

Showing 34 out of 34 atomic motifs.

Group(s)
crtRnor#(name) [p-value]
Motif
craRnor#
Discovery
p-value
Location Width (+)motif (-)motif
0 annotated groups

0 'de novo' group(s)
36521 1.15E-01 chr20:35,421,505-35,421,516 12  Seq Logo
TTwAAATTTGCT
Seq Logo
AGCAAATTTsAA
0 annotated groups

0 'de novo' group(s)
36575 1.25E-01 chr20:35,421,953-35,421,962 10  Seq Logo
nyTTTAAATA
Seq Logo
TATTTAAArn
0 annotated groups

0 'de novo' group(s)
36623 2.22E-01 chr20:35,422,122-35,422,133 12  Seq Logo
ACTryAAnTTTw
Seq Logo
sAAAnTTryAGT
0 annotated groups

1 'de novo' group(s)
9242
36693 1.07E-01 chr20:35,422,207-35,422,218 12  Seq Logo
TTCmCTTCTTTw
Seq Logo
sAAAGAAGkGAA
0 annotated groups

0 'de novo' group(s)
36726 7.54E-02 chr20:35,422,682-35,422,695 14  Seq Logo
ksAyATAAAGTTGn
Seq Logo
nCAACTTTATrTwm
0 annotated groups

1 'de novo' group(s)
2167
36762 1.62E-01 chr20:35,422,718-35,422,725 8  Seq Logo
GGAGGAGG
Seq Logo
CCTCCTCC
0 annotated groups

1 'de novo' group(s)
6955
36854 1.14E-01 chr20:35,422,840-35,422,851 12  Seq Logo
ATTwArATGAwA
Seq Logo
TsTCATyTsAAT
0 annotated groups

0 'de novo' group(s)
36804 1.07E-01 chr20:35,422,844-35,422,855 12  Seq Logo
AAAknGTAAnTT
Seq Logo
AAnTTACnmTTT
0 annotated groups

1 'de novo' group(s)
11883
36898 1.08E-01 chr20:35,422,845-35,422,856 12  Seq Logo
AAwGmAAAATTG
Seq Logo
CAATTTTkCsTT
0 annotated groups

0 'de novo' group(s)
36943 7.80E-02 chr20:35,422,846-35,422,857 12  Seq Logo
ATGnwAAATTGT
Seq Logo
ACAATTTsnCAT
0 annotated groups

0 'de novo' group(s)
36974 7.90E-02 chr20:35,422,847-35,422,858 12  Seq Logo
wGmAAAATTGTw
Seq Logo
sACAATTTTkCs
0 annotated groups

0 'de novo' group(s)
37002 7.44E-02 chr20:35,422,850-35,422,863 14  Seq Logo
TTACTTGTTGGCnw
Seq Logo
snGCCAACAAGTAA
0 annotated groups

1 'de novo' group(s)
11883
37033 9.33E-02 chr20:35,422,919-35,422,930 12  Seq Logo
CAATGTTTCAnT
Seq Logo
AnTGAAACATTG
0 annotated groups

0 'de novo' group(s)
37073 1.03E-01 chr20:35,423,003-35,423,012 10  Seq Logo
AAAACTTACT
Seq Logo
AGTAAGTTTT
0 annotated groups

1 'de novo' group(s)
6305
37103 2.23E-01 chr20:35,423,098-35,423,111 14  Seq Logo
CCTTTGTTAATTGT
Seq Logo
ACAATTAACAAAGG
0 annotated groups

1 'de novo' group(s)
14259
37150 7.82E-02 chr20:35,423,237-35,423,252 16  Seq Logo
TTTGTTwATTGTCyTT
Seq Logo
AArGACAATsAACAAA
0 annotated groups

1 'de novo' group(s)
11679
37193 1.13E-01 chr20:35,423,255-35,423,267 13  Seq Logo
CTTTCATTwrGrG
Seq Logo
CyCysAATGAAAG
0 annotated groups

0 'de novo' group(s)
37259 6.01E-02 chr20:35,423,294-35,423,302 9  Seq Logo
CCCTCCnCC
Seq Logo
GGnGGAGGG
0 annotated groups

1 'de novo' group(s)
2133
37337 5.49E-03 chr20:35,423,342-35,423,347 6  Seq Logo
ATTTTA
Seq Logo
TAAAAT
0 annotated groups

0 'de novo' group(s)
37417 1.16E-01 chr20:35,423,440-35,423,451 12  Seq Logo
AACTTkATmTyk
Seq Logo
mrAkATmAAGTT
0 annotated groups

1 'de novo' group(s)
12919
37857 1.31E-01 chr20:35,423,554-35,423,569 16  Seq Logo
AGTTGAGTCAGTGGCT
Seq Logo
AGCCACTGACTCAACT
0 annotated groups

1 'de novo' group(s)
3705
37465 5.49E-03 chr20:35,423,556-35,423,563 8  Seq Logo
TTGAGTCA
Seq Logo
TGACTCAA
0 annotated groups

0 'de novo' group(s)
37529 5.49E-03 chr20:35,423,556-35,423,565 10  Seq Logo
TTGAGTCAGT
Seq Logo
ACTGACTCAA
0 annotated groups

0 'de novo' group(s)
37610 5.49E-03 chr20:35,423,557-35,423,566 10  Seq Logo
TGAGTCAGTG
Seq Logo
CACTGACTCA
0 annotated groups

1 'de novo' group(s)
5377
37688 5.49E-03 chr20:35,423,558-35,423,565 8  Seq Logo
GAGTCAGT
Seq Logo
ACTGACTC
0 annotated groups

0 'de novo' group(s)
37768 5.49E-03 chr20:35,423,561-35,423,570 10  Seq Logo
TCAGTGGCTT
Seq Logo
AAGCCACTGA
0 annotated groups

0 'de novo' group(s)
38426 5.49E-03 chr20:35,423,566-35,423,588 23  Seq Logo
GGCTTGAAACTTTTAAA...
Seq Logo
AGAGCTTTTAAAAGTTT...
0 annotated groups

0 'de novo' group(s)
37929 5.49E-03 chr20:35,423,570-35,423,577 8  Seq Logo
TGAAACTT
Seq Logo
AAGTTTCA
0 annotated groups

1 'de novo' group(s)
167
38013 5.49E-03 chr20:35,423,574-35,423,581 8  Seq Logo
ACTTTTAA
Seq Logo
TTAAAAGT
0 annotated groups

1 'de novo' group(s)
5273
38106 5.49E-03 chr20:35,423,575-35,423,580 6  Seq Logo
CTTTTA
Seq Logo
TAAAAG
0 annotated groups

1 'de novo' group(s)
5103
38196 5.49E-03 chr20:35,423,576-35,423,581 6  Seq Logo
TTTTAA
Seq Logo
TTAAAA
0 annotated groups

1 'de novo' group(s)
5103
38276 5.49E-03 chr20:35,423,578-35,423,583 6  Seq Logo
TTAAAA
Seq Logo
TTTTAA
0 annotated groups

1 'de novo' group(s)
7116
38349 5.49E-03 chr20:35,423,579-35,423,586 8  Seq Logo
TAAAAGCT
Seq Logo
AGCTTTTA
0 annotated groups

1 'de novo' group(s)
10784
38497 5.49E-03 chr20:35,423,593-35,423,607 15  Seq Logo
TCCAAGTwAGAAAAA
Seq Logo
TTTTTCTsACTTGGA

Questions or comments: cisred@bcgsc.ca